Protein Alignment KLK4 and epsilonTry

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 85/265 - (32%)
• Similarity: 124/265 - (46%)
• Gaps: 42/265 - (15%)

Human    12 LGYLILGVAGSLVSGSCSQ----IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72
            |..|...:||::..|...|    |:.|.:.|..:.|:|.:|......||.|.:.....|::||||
  Fly     8 LSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDIVITAAHC 72

Human    73 FQNSYTIGLGLHSLEADQ---EPGSQMVEASLSV-------RHPEYNRPLLANDLMLIKLDESVS 127
            .|          |:||..   ..||....:..||       .|..||...:.||:.:|:::..:|
  Fly    73 LQ----------SIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLS 127

Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC--------SKLY 182
            ...:||.|.||...|..|.:.:|||||...:|  .:|..|..|::.::....|        .|:.
  Fly   128 FRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIK 192

Human   183 DPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            |     :|.||..  ..||:|.|||||||:....|.|:||:|.. ||.|..||||.::..|.|||
  Fly   193 D-----TMLCAYA--PHKDACQGDSGGPLVSGDRLVGVVSWGYG-CGDVRYPGVYADVAHFHEWI 249

Human   248 EKTVQ 252
            |:|.:
  Fly   250 ERTAE 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	78/238 (33%)
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	75/236 (32%)