Protein Alignment KLK4 and Jon99Ciii

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_733330.1
• Gene: Jon99Ciii / 43543
• FlyBaseID: FBgn0003357
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 72/258 - (27%)
• Similarity: 114/258 - (44%)
• Gaps: 30/258 - (11%)

Human    14 YLILGVAGSLVSGSCSQ-------------IINGEDCSPHSQPWQAALVM--ENELFCSGVLVHP 63
            :|.|.||.:....:.:|             |.||........|:...|:.  ....:|.|.::..
  Fly     6 FLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGN 70

Human    64 QWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSE 128
            .|||:||||...:..:.:...:....|...:..|.:...::|..||...|.||:.||:... |..
  Fly    71 TWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGSGDIIQHHHYNSGNLHNDISLIRTPH-VDF 134

Human   129 SDTIRSISIASQCPT----AGNSCLVSGWGLLANGR-MPTVLQCVNVSVVSEEVCSKLYDPLYHP 188
            ...:..:.:.|....    ||...:.||||...:|. :|..||.|:|.::|:..||:.:.  .|.
  Fly   135 WSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSPLPDWLQSVDVQIISQSDCSRTWS--LHD 197

Human   189 SMFC--AGGGQDQKDSCNGDSGGPLICN--GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            :|.|  ..||   |.:|.|||||||:.:  ..|.|:.|||.|...|.|.|.|::.:..:.:||
  Fly   198 NMICINTDGG---KSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSGAPAVFSRVTGYLDWI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	67/228 (29%)
Jon99Ciii	NP_733330.1	Tryp_SPc	36..260	CDD:238113	67/228 (29%)