Protein Alignment KLK4 and CG4053

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 77/260 - (29%)
• Similarity: 137/260 - (52%)
• Gaps: 38/260 - (14%)

Human    15 LILGVAGSLVSGS--------CSQIINGEDCSPHSQPWQAAL--VMENELFCSGVLVHPQWVLSA 69
            |:||.:..:..|.        .::|:.|::......|:|.::  :.:..: ||||:::.||:|:|
  Fly    11 LLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHI-CSGVILNEQWILTA 74

Human    70 AHCFQNSYTIGLGLHSLEA-----DQ-EPGSQMVEASLSVRHPEYNRP-LLANDLMLIKLDESVS 127
            .||     .:...:..|..     |: |||..:......| |..|:.| :..||:.||.::||:.
  Fly    75 GHC-----ALDFSIEDLRIIVGTNDRLEPGQTLFPDEALV-HCLYDIPYVYNNDIALIHVNESII 133

Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTV--LQCVNVSVVSEEVCSKLYD-----PL 185
            .:|..:.:.::.:.|.||::..::||| ......|||  ||.:|:::::.|.|.:.:|     .:
  Fly   134 FNDRTQIVELSREQPPAGSTVTLTGWG-APESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDI 197

Human   186 YHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250
            .|...|...|    :.:|:|||||||:..|.|.|||::|:| || ||:|.:|.|...:.:||.:|
  Fly   198 GHICTFTREG----EGACSGDSGGPLMWEGKLVGLVNWGRA-CG-VGMPDMYANTVYYQDWIRRT 256

Human   251  250
              Fly   257  256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	72/234 (31%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	72/234 (31%)