Protein Alignment KLK4 and Sb

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 79/254 - (31%)
• Similarity: 127/254 - (50%)
• Gaps: 38/254 - (14%)

Human    29 SQIINGEDCSPHSQPWQAALVMENELF-------CSGVLVHPQWVLSAAHCFQ----NSYTIGLG 82
            ::|:.|:..:....|||.: |.....|       |.|.|::..|:.:|.||..    :...|.:|
  Fly   542 TRIVGGKSAAFGRWPWQVS-VRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVG 605

Human    83 LHSLEADQEPGSQM--VEASLS--VRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI-ASQCP 142
            .:.....||   |:  :|..::  |.||:|:......||.|:||::.:..:..:..|.: .:...
  Fly   606 EYDFSHVQE---QLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDSL 667

Human   143 TAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLY----DPLYHPSMF-CAG---GGQD 198
            ..|.:..|:|||.|: .|.:|:|||.|:|.:||.:.|..::    ...:.|.:| |||   |||
  Fly   668 LIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQ- 731

Human   199 QKDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
              |||.|||||||....     :|.|::|:| ..|.:..:|||.|.:.|||.||.:.|:
  Fly   732 --DSCQGDSGGPLQAKSQDGRFFLAGIISWG-IGCAEANLPGVCTRISKFTPWILEHVR 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	78/248 (31%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	78/248 (31%)