Protein Alignment KLK4 and Jon74E

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 80/267 - (29%)
• Similarity: 125/267 - (46%)
• Gaps: 42/267 - (15%)

Human    12 LGYLILGVAGSLVS------GSCSQIINGEDCSPHSQPWQAALVME--NELF--CSGVLVHPQWV 66
            |.:|::.|.|..:|      |...:|..||....:..|:|..|.:|  |:::  |...|:..:::
  Fly     7 LVFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYL 71

Human    67 LSAAHCFQN----SYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVS 127
            |:||||.:.    :|.:| |:..|...|...|...|..|   ||::|...|.||:.|::|.|...
  Fly    72 LTAAHCVEKAVAITYYLG-GVLRLAPRQLIRSTNPEVHL---HPDWNCQSLENDIALVRLPEDAL 132

Human   128 ESDTIRSISIASQCPTAGNS-----CLVSGWGLLANGRMPTV---LQCVNVSVVSEEVCSKLYDP 184
            ..|:||.|.:.. ..::.||     .:.||||.: |.....:   |:.|...|.|.|.|...|..
  Fly   133 LCDSIRPIRLPG-LSSSRNSYDYVPAIASGWGRM-NDESTAISDNLRYVYRFVESNEDCEYSYAN 195

Human   185 LYHPSMFC---AGGGQDQKDSCNGDSGGPLICNGYLQ------GLVSFGKAPCGQVGVPGVYTNL 240
            : .|:..|   .||    |.:|.|||||||:.:..:|      |:.|:||......|.|.|:|.:
  Fly   196 I-KPTNICMDTTGG----KSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRI 255

Human   241 CKFTEWI 247
            ..:.:||
  Fly   256 TAYLDWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/242 (31%)
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	72/241 (30%)