Protein Alignment KLK4 and CG4914

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_648711.1
• Gene: CG4914 / 39597
• FlyBaseID: FBgn0036436
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 242
• Identity: 75/242 - (30%)
• Similarity: 117/242 - (48%)
• Gaps: 30/242 - (12%)

Human    29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSLEAD 89
            |:|:.|........||.|.|...|..:|.|.|::.::||:||||.:.    ...:..|.|....|
  Fly   126 SRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCND 190

Human    90 QE-PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI----ASQCPTAGNSCL 149
            :| |.::.|..:.|.:....|   ..||:.|::|::.|..:..||.|.:    ..|....|...:
  Fly   191 KERPETRFVLRAFSQKFSFSN---FDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAI 252

Human   150 VSGWGLL-ANGRMPTVLQCVNVSVVSEEVC---SKLYDPLYHPSMFCAG----GGQDQKDSCNGD 206
            .:|||.| .:|:...:||.|.|.|:..:.|   :.....:...:|.|:|    ||   :|||.||
  Fly   253 ATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGG---RDSCQGD 314

Human   207 SGGPLI-----CNGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            |||||:     ...:.| |:||:|.. |.:...|||||.:.|:.:||
  Fly   315 SGGPLVRLRPDDKRFEQIGIVSWGNG-CARPNYPGVYTRVTKYLDWI 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/240 (31%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	74/240 (31%)