Protein Alignment KLK4 and CG4477

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_648295.1
• Gene: CG4477 / 39058
• FlyBaseID: FBgn0035971
• Length: 315
• Species: Drosophila melanogaster
• Alignment Length: 216
• Identity: 60/216 - (27%)
• Similarity: 95/216 - (43%)
• Gaps: 22/216 - (10%)

Human    55 FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL--------EADQEPGSQMVEASLSVRHPEYNRP 111
            |||||::.|.:|:::|||..|...:.:....|        .....|....|.....:..|:....
  Fly    71 FCSGVILAPMFVMTSAHCLINKRRVLISSRVLLIVAGTLNRLKYIPNRTFVTPVTHIWLPDSFTM 135

Human   112 LLANDLMLIKLDESVSESDTIRSISIAS---QCPTAGNSCLVSGWG-LLANGRMPTVLQCVNVSV 172
            ....|..|:|:......::  ..||||.   ..|..|..|.|.||| :...|.:.:.:..::|.|
  Fly   136 RNKQDFGLLKVKNPFPRNN--EHISIARLPVHPPLPGLKCKVMGWGRMYKGGPLASYMLYIDVQV 198

Human   173 VSEEVCSKLYDPLYHPSM--FCAGGGQD--QKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGV 233
            :..|.|:|.   |..||:  .||....|  .:..|.||.|.|::.||.:.|:|:. .|.||...:
  Fly   199 IDSEACAKW---LRVPSVEHVCAVDSDDLTAQQPCGGDWGAPMLHNGTVYGIVTI-LAGCGVSHL 259

Human   234 PGVYTNLCKFTEWIEKTVQAS 254
            |.:|||:.....||.:.:.:|
  Fly   260 PSLYTNVHSNANWIHEKIISS 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	59/210 (28%)
CG4477	NP_648295.1	Tryp_SPc	55..276	CDD:238113	59/210 (28%)