Protein Alignment KLK4 and CG32374

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_729270.1
• Gene: CG32374 / 38848
• FlyBaseID: FBgn0052374
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 76/233 - (32%)
• Similarity: 116/233 - (49%)
• Gaps: 16/233 - (6%)

Human    29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC---FQNSYTIGLGLHSLEADQ 90
            ::|:||:.......|:|.||...|...|..|:::.:|:|:|.||   ....||:..|    ...|
  Fly    72 TRIVNGKKIKCSRAPYQCALHYNNYFICGCVILNRRWILTAQHCKIGNPGRYTVRAG----STQQ 132

Human    91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC-LVSGWG 154
            ..|.|:.....:|.||.|:...:.|||.::||...::....::.:.:.|........| |.||||
  Fly   133 RRGGQLRHVQKTVCHPNYSEYTMKNDLCMMKLKTPLNVGRCVQKVKLPSTRTKRFPKCYLASGWG 197

Human   155 LL-ANGR-MPTVLQCVNVSVVSEEVCSKLYDPL---YHPSMFCAGGGQDQKDSCNGDSGGPLICN 214
            |. ||.: :...|:.|.|..||...|.:.|...   .:..|.||  .:..:|:|:|||||||:.|
  Fly   198 LTSANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICA--KRKNRDTCSGDSGGPLVHN 260

Human   215 GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
            |.|.|:.||| ..|.....||||.|:.::|.||:|..:
  Fly   261 GVLYGITSFG-IGCASAKYPGVYVNVLQYTRWIKKVAK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	75/227 (33%)
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	73/225 (32%)