Protein Alignment KLK4 and CG10472

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Alignment Length: 249
• Identity: 76/249 - (30%)
• Similarity: 120/249 - (48%)
• Gaps: 29/249 - (11%)

Human    22 SLVSGSCSQIINGEDCSPHSQPWQAALVM---ENELFCSGVLVHPQWVLSAAHCFQNSYTIG--- 80
            :|.||   :|..|:...|:..|:|..|::   ....:|.|.::..:|:::|||| .:|.|.|
  Fly    41 TLPSG---RITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHC-TDSLTTGVDV 101

Human    81 -LGLHSLEADQEPGSQM--VEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA---- 138
             ||.|.....:|.|.|:  ||....:.|.::....:.||:.||||...:..:..|:...:.
  Fly   102 YLGAHDRTNAKEEGQQIIFVETKNVIVHEDWIAETITNDISLIKLPVPIEFNKYIQPAKLPVKSD 166

Human   139 SQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC---AGGGQD 198
            |.....|.:.:.||||.:::..  ...:||...|.:::...||..|..|...|..|   .||
  Fly   167 SYSTYGGENAIASGWGKISDSATGATDILQYATVPIMNNSGCSPWYFGLVAASNICIKTTGG--- 228

Human   199 QKDSCNGDSGGPLIC---NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249
             ..:|||||||||:.   :..|.|..|||.|...:||.|||:|.:..:.:|||:
  Fly   229 -ISTCNGDSGGPLVLDDGSNTLIGATSFGIALGCEVGWPGVFTRITYYLDWIEE 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/240 (30%)
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	70/237 (30%)