Protein Alignment KLK4 and CG6592

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 241
• Identity: 63/241 - (26%)
• Similarity: 110/241 - (45%)
• Gaps: 28/241 - (11%)

Human    30 QIINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHC--FQNSYTIGLGLHSLEAD 89
            :|..|:..:||..|:|..::::..   .:|.|.|:..:.|::||||  ......:.||.:.::..
  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKNA 186

Human    90 QEPGS--QMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--------A 144
            :|.|.  .||.:.....:|.:|...|.:|:.:::|..:||.::.|..|    |.|.        .
  Fly   187 KEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPI----QLPKRHYEYRSFK 247

Human   145 GNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDS 207
            ....:.||||..|.|  .:..||:.|.:.::....|...:...|..:..|. .|::.:.:|||||
  Fly   248 NKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICT-SGRNARSTCNGDS 311

Human   208 GGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            ||||:.      ...|.|:.|||.......|.|..:|.:..:.:||
  Fly   312 GGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWI 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	63/240 (26%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	63/240 (26%)