Protein Alignment KLK4 and CG32277

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_728835.1
• Gene: CG32277 / 38393
• FlyBaseID: FBgn0052277
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 79/274 - (28%)
• Similarity: 117/274 - (42%)
• Gaps: 55/274 - (20%)

Human    15 LILGVA-------GSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72
            |::|:|       .||.:....:|..|:........:...|....:..|.||::.|..||:||||
  Fly     4 LLIGLALLHQLEGSSLFTLRQGKIFGGKTTLVKDHSFLVNLRRGGKFRCGGVIISPNCVLTAAHC 68

Human    73 FQNSY--TIGLGLHSLE---ADQEPGSQMVEASLSVRHPEY-NRPLLANDLMLIKLDESVSESDT 131
            .:..|  ...|.:|:.:   .|..|...:..|......|.| .:..|.:||.:|:|.
  Fly    69 LEGRYQQVRDLTVHAQQQCLGDDMPPEHVRSAWYVGLSPNYCAQRGLDSDLAVIRLS-------- 125

Human   132 IRSISIASQCPTAGNSCLVS---------------GWGLLANGRMPTVLQCV---NVSVVSEEVC 178
             |...|      |||:.||.               |||.: |.:.....||:   ||.::|...|
  Fly   126 -RPFDI------AGNASLVKIDYNDLPPHSNLTVLGWGAI-NEQGHNWNQCLQEANVKLISHREC 182

Human   179 SKLYDPLYHP---SMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL 240
            .|.....:..   :|||| .|::.:|:|.||||||.|..|...|:||:|.. ||. |.|||||.|
  Fly   183 IKSVGSGWQKVTNNMFCA-LGKNARDACQGDSGGPAIYAGRSVGIVSWGYG-CGS-GYPGVYTRL 244

Human   241 C--KFTEWIEKTVQ 252
            .  ..|.|::..::
  Fly   245 SSPSITYWLKDFIE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/247 (30%)
CG32277	NP_728835.1	Tryp_SPc	27..246	CDD:238113	72/237 (30%)