Protein Alignment KLK4 and CG3650

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 74/262 - (28%)
• Similarity: 119/262 - (45%)
• Gaps: 44/262 - (16%)

Human    12 LGYLILGVAGS-----LVSGSCSQI--INGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSA 69
            |..|:||:|..     :|.|:.:.:  :.|         :...|..:...:|.|.||....|::|
  Fly    10 LTQLLLGLASGQIQPRIVGGTTTTLSAVGG---------FVVNLRYDGTFYCGGSLVTSSHVVTA 65

Human    70 AHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRH------PE-YNRPLLANDLMLIKLDESVS 127
            |||.:       |..:.....:.|...:..|..||.      |. ::...|..|:.:|:|..:::
  Fly    66 AHCLK-------GYQASRITVQGGVSKLSQSGVVRRVARYFIPNGFSSSSLNWDVGVIRLQSALT 123

Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGL--LANGRMPTVLQCVNVSVVSEEVCSKLY---DPLYH 187
            .|. |.:|.:.......||...|||||.  ..|......|:.|.:.::.::||.:.|   |.| .
  Fly   124 GSG-ITTIPLCQVQWNPGNYMRVSGWGTTRYGNSSPSNQLRTVRIQLIRKKVCQRAYQGRDTL-T 186

Human   188 PSMFCA--GGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250
            .|.|||  ||    ||||:|||||.:|....|.|:||:|.. |.....|||||::.:...:|.::
  Fly   187 ASTFCARTGG----KDSCSGDSGGGVIFKNQLCGIVSWGLG-CANAQYPGVYTSVHRVRSFILRS 246

Human   251 VQ 252
            ::
  Fly   247 IK 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	67/234 (29%)
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	68/240 (28%)