Protein Alignment KLK4 and Ser8

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 241
• Identity: 75/241 - (31%)
• Similarity: 119/241 - (49%)
• Gaps: 19/241 - (7%)

Human    19 VAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTI-GLG 82
            :.|.:|.|:.|.|   ||     :|||.:|......||.|.::....:::||||.....|: .|.
  Fly    31 LGGRIVGGTASSI---ED-----RPWQVSLQRSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNLR 87

Human    83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS 147
            :.:....:..|..:||.:....|..||.....||:.:::|...::...||::|::||..|..|::
  Fly    88 IRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTFGSTIKAITMASATPAHGSA 152

Human   148 CLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKL---YDPLYHPSMFCAGGGQDQKDSCNGDSG 208
            ..:||||..: :|.....|..|:..:|....|...   |......:|.||..  ..||:|.||||
  Fly   153 ASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAAA--TNKDACQGDSG 215

Human   209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI---EKTV 251
            |||:..|.|.|:||:|: .|.....||||.|:.:..:|:   :|||
  Fly   216 GPLVSGGQLVGVVSWGR-DCAVANYPGVYANIAELRDWVLQAQKTV 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	68/226 (30%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	70/228 (31%)