Protein Alignment KLK4 and gammaTry

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_725034.1
• Gene: gammaTry / 36221
• FlyBaseID: FBgn0010359
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 80/251 - (31%)
• Similarity: 123/251 - (49%)
• Gaps: 18/251 - (7%)

Human    12 LGYLIL------GVAGSLVSGSCSQ----IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWV 66
            |.::||      .:.|::..|...|    |:.|...:..|.|||.:|.......|.|.:.....:
  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66

Human    67 LSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDT 131
            ::||||.|:.....|.:.:..:....|......|....|..||...:.||:.:||::.:::.|.|
  Fly    67 VTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSST 131

Human   132 IRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKL---YDPLYHPSMF 191
            |::|.:||..|..|.:..|||||.|:.|  .:|:.||.|||::||:..|:..   |......:|.
  Fly   132 IKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMI 196

Human   192 CAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            ||..  ..||:|.|||||||:..|.|.|:||:|.. |.....||||.::.....|:
  Fly   197 CAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/222 (33%)
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	73/221 (33%)