Protein Alignment KLK4 and CG8170

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 82/316 - (25%)
• Similarity: 125/316 - (39%)
• Gaps: 83/316 - (26%)

Human    10 WFLGYLILGVAGSLVSGSC---------------------------------------------- 28
            |..|.||.|....|:.|.|
  Fly   543 WLSGGLIQGTCDGLLRGCCHRTAKSANLGSSDFVGNAVDLTDLPQKNYGPVNNEPSCGISLAKQT 607

Human    29 --SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHSLE 87
              .:|:.|:|....|.||||.:.:.:.. |.|.|:..:.|::|.||...:    ..:.||.:.:.
  Fly   608 AQRRIVGGDDAGFGSFPWQAYIRIGSSR-CGGSLISRRHVVTAGHCVARATPRQVHVTLGDYVIN 671

Human    88 ADQEPGSQMVEASLSVR----HPEYNRPLLAN--DLMLIKLDESVSESDTIRSISIASQCPTAGN 146
            :..||   :...:..||    ||.:.....|:  |:.::.|:.:|.....|..|.:    |....
  Fly   672 SAVEP---LPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIAPICL----PEKNE 729

Human   147 SCL-----VSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLY-----DPLYHPSMFCAGGGQDQ 199
            ..|     .:|||.|..|.  .|..||.|:|.|:...:|.:.:     :.:.:..|.|||.....
  Fly   730 DFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYRNGG 794

Human   200 KDSCNGDSGGPLI--CNG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
            ||||.|||||||:  .||  ||.|:||.|.: |...|.||:|.::.|..:|:...|
  Fly   795 KDSCQGDSGGPLMHDKNGRWYLIGVVSAGYS-CASRGQPGIYHSVSKTVDWVSYVV 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/244 (30%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	73/242 (30%)