Protein Alignment KLK4 and Send2

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_609708.2
• Gene: Send2 / 34836
• FlyBaseID: FBgn0264253
• Length: 239
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 69/240 - (28%)
• Similarity: 110/240 - (45%)
• Gaps: 26/240 - (10%)

Human    14 YLILGVAGSLVSGSC----SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
            :|:|....||.:|..    .:||.|:.......|||.::..:.:..|.|.:.....:::||||.|
  Fly     6 FLLLLALNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITAAHCVQ 70

Human    75 -NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA 138
             ..|.:..|    .|.:.....:|:.:....|..     |.||:.:::|.:.:..::.::.|.:|
  Fly    71 GQGYQVRAG----SALKNSNGSVVDVAAIRTHEG-----LGNDIAIVRLSKPLEFTNQVQPIPLA 126

Human   139 SQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG-GQDQKDS 202
            ...|..|:...|||||..:....|..||.||:.:.....|.     |..||..|||. |   :.:
  Fly   127 KTNPPPGSIAFVSGWGSSSYYSHPIDLQGVNLYIQWPYYCG-----LTEPSRICAGSFG---RAA 183

Human   203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247
            |.|||||||:.:..|.|:||.|...|   ....:||::..|.|||
  Fly   184 CKGDSGGPLVFDQQLVGVVSGGTKDC---TYSSIYTSVPYFREWI 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	64/219 (29%)
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	62/218 (28%)