Protein Alignment KLK4 and Phae2

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 64/263 - (24%)
• Similarity: 108/263 - (41%)
• Gaps: 44/263 - (16%)

Human    15 LILGVAGSLVSGSC-----SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
            |:|.|..|..||..     .:::.|:..:.:|.|:..::......:|:..:::..|:::||||..
  Fly    11 LLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLA 75

Human    75 NSYTIGLGLHSLEADQEPGSQMVEASLSVR----------------HPEYNRPLLANDLMLIKLD 123
            |            .:|..||.:|..|::|.                :..|....:..|:.||...
  Fly    76 N------------RNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTP 128

Human   124 ESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMP----TVLQCVNVSVVSEEVC-----S 179
            .:.:.:..:..:.:.|..........:.|||..:....|    |:.:..|:.::|.:.|     |
  Fly   129 TAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGS 193

Human   180 KLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244
            |..|  .|.:..|.|........|..||||||:....|.|:||:||.||||...|.||..:..|.
  Fly   194 KGQD--VHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFI 256

Human   245 EWI 247
            .||
  Fly   257 TWI 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	58/242 (24%)
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	58/242 (24%)