Protein Alignment KLK4 and CG11911

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 70/261 - (26%)
• Similarity: 124/261 - (47%)
• Gaps: 34/261 - (13%)

Human    15 LILGVAGSLVSGSCSQ---------IINGEDCSPHSQPWQAALV---MENELFCSGVLVHPQWVL 67
            |:....|:.:|...::         :|||.:..|||.|:..:|.   :::...|.|.|::..|::
  Fly    12 LVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGTLINKDWIV 76

Human    68 SAAHCFQNSYTIGL----GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSE 128
            :||||.  |..:|:    |||: .|:.:..:|..:......|.:|...:...|:.|:.::||...
  Fly    77 TAAHCI--SEPVGMSIIAGLHT-RAEVDELTQQRQVDFGRVHEKYTGGVGPYDIALLHVNESFIF 138

Human   129 SDTIRSISIASQCPTAGNSCLVSGWG----LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP- 188
            ::.::..::.|:.........:.|||    .:.:|  ...||.|...:::.|.|.:.. |...|
  Fly   139 NEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSG--AKTLQTVTTQILNYEECKEEL-PESAPI 200

Human   189 --SMFCAGGGQDQKDSCNGDSGGPLICN-----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEW 246
              |..|:...|..|.:|||||||||:..     ..|.|:||:|..|||...:|.:||.:..:.:|
  Fly   201 AESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDW 265

Human   247 I 247
            |
  Fly   266 I 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	67/236 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	65/234 (28%)