Protein Alignment KLK4 and sphe

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 64/247 - (25%)
• Similarity: 113/247 - (45%)
• Gaps: 15/247 - (6%)

Human    15 LILGVAGSLVSGSC---SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS 76
            :|||:.|....|.|   .:|:.|||....:..:.|:|.::|...|.|.::....:|:.|||....
  Fly     7 VILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRD 71

Human    77 YTI----GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI 137
            ..:    .|.......:|..|.::|.......||:|..  |.|:|.:|.|...::.:|.|.:|.:
  Fly    72 GKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYN--LNNNLAVITLSSELTYTDRITAIPL 134

Human   138 ASQ---CPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQ 199
            .:.   .|..|:..:|:|||..::|.....::.:::.|..|..|...|.. :....||. ..:.:
  Fly   135 VASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAYSD-HDEQSFCL-AHELK 197

Human   200 KDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
            :.:|:||.||..|....|.||.:|....||. ..|.|:..|..:.:||::.:
  Fly   198 EGTCHGDGGGGAIYGNTLIGLTNFVVGACGS-RYPDVFVRLSSYADWIQEQI 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	58/225 (26%)
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	53/209 (25%)