Protein Alignment KLK4 and CG32376

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 74/233 - (31%)
• Similarity: 114/233 - (48%)
• Gaps: 18/233 - (7%)

Human    29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---QNSYTIGLGLHSLEADQ 90
            ::|:||:.......|:|.:|..|....|..|:::..|:|:|.|||   ...||:.:|     :||
  Fly    64 TRIVNGKRIPCTEAPFQGSLHYEGYFVCGCVIINKIWILTAHHCFFGPPEKYTVRVG-----SDQ 123

Human    91 E-PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-GNSCLVSGW 153
            : .|.|:......|....||...:.:||.::||...|.....:|.:.:.|...|. ....:||||
  Fly   124 QRRGGQLRHVKKIVALAAYNDYTMRHDLAMMKLKSPVYFGKCVRPVKLPSTKTTKFPKKFVVSGW 188

Human   154 GLL-ANGR-MPTVLQCVNVSVVSEEVCSKLYDPL---YHPSMFCAGGGQDQKDSCNGDSGGPLIC 213
            |:. ||.: :...|:.|.:..:....|.|:|...   .:..|.||  .:..||||:|||||||..
  Fly   189 GITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICA--SRTNKDSCSGDSGGPLTS 251

Human   214 NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
            .|.|.|:||:| ..|.....||||.|..::..||:|.:
  Fly   252 RGVLYGIVSWG-IGCANKNYPGVYVNCKRYVPWIKKVI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/228 (32%)
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	71/226 (31%)