Protein Alignment KLK4 and CG14780

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 81/266 - (30%)
• Similarity: 123/266 - (46%)
• Gaps: 36/266 - (13%)

Human    10 WFLGYLILGVAGSLVSGSCSQIINGE----DCSPHSQPWQAALVMENELF-----CSGVLVHPQW 65
            ||   |:...|..|.....|:||||.    |.:.|..  ...|:..:..|     |.|.|:.|:.
  Fly    15 WF---LLACAAADLQENQQSRIINGSVAKADETRHLV--SIRLLRHDNNFGSGHICGGALIAPRK 74

Human    66 VLSAAHCFQNS----------YTIGLGLHSLEADQEPGSQMVE--ASLSVRHPEYNRPLLANDLM 118
            ||:||||..|:          :.:.||  :|...:.....:|.  :|::..| .::...:.:|:.
  Fly    75 VLTAAHCLYNNQRKRFRRASEFVVVLG--TLNRFEHRNGTIVSQVSSMAYMH-TFSPDSMRDDVG 136

Human   119 LIKLDESVSESD------TIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEV 177
            ::.|...:..|.      |:..|.:|.|....|..|.|:|||......:..:|...|||.:..:.
  Fly   137 ILFLRTGLPMSPGGGVHLTVAPIQLAGQITPPGKLCQVAGWGRTEQSSLSNILLTANVSTIRHQT 201

Human   178 CSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCK 242
            |..:|.....|.|.|||..|...|||.|||||||:..|.|.|:||:|.. |.:.|:||||.::..
  Fly   202 CRMIYRSGLLPGMMCAGRLQGGTDSCQGDSGGPLVHEGRLVGVVSWGYG-CAEPGLPGVYVDVEY 265

Human   243 FTEWIE 248
            :.:|||
  Fly   266 YRQWIE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	75/245 (31%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	73/243 (30%)