Protein Alignment KLK4 and CG33461

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 73/293 - (24%)
• Similarity: 122/293 - (41%)
• Gaps: 74/293 - (25%)

Human    11 FLGYLILGVAGS---LVSGSCS-------QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQW 65
            :|...:|||.||   .:..:|.       :||||........||.|.|.......|:|.|::..:
  Fly    12 YLALFVLGVHGSSSVFLEENCGVVPRLSYKIINGTPARLGRYPWMAFLHTPTYFLCAGSLINQWF 76

Human    66 VLSAAHCFQNSYTI--GLGLHS------------LEADQEPGSQMVEASLSVRHPEYNRPLLAND 116
            ||::|||.::...:  .||.::            |||.||....|:     .:|..|:....:||
  Fly    77 VLTSAHCIEDDVELIARLGENNRDNDIDCENNRCLEATQEYNVDML-----FKHRLYDPKDFSND 136

Human   117 LMLIKLDESVSESDTIRSISIASQCPTAGNSCL-----------------VSGWGLLA---NGRM 161
            :.:::|:..|..:..|:.|            |:                 .:||||.:   |.:.
  Fly   137 IGMLRLERRVEYTYHIQPI------------CIFHHRRMQLVVDQITWFKATGWGLTSTDLNTKS 189

Human   162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP-----LI--CNGYLQ- 218
            ..||..:|:.......|::::...:.....||  |.|..:.|.||||||     ||  ...::|
  Fly   190 SRVLMELNLYRRPRNDCARIFKQNFLSGQICA--GNDDGNLCRGDSGGPQGRYVLIFGMKRFVQM 252

Human   219 GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
            |:.||....|.:|   .:.|::.::..||:|.|
  Fly   253 GIASFTYENCSKV---SILTDVVRYGRWIKKVV 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	64/260 (25%)
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	62/258 (24%)