Protein Alignment KLK4 and CG43336

DIOPT Version :10

• Sequence 1: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 81/280 - (28%)
• Similarity: 117/280 - (41%)
• Gaps: 60/280 - (21%)

Human    12 LGYLILGVAGSLV-----------SGSCSQIINGEDCSPHSQPWQAAL-VMENELFCSGVLVHPQ 64
            |.:.:|.:.||..           |.|..::.||...|..|.||.|.| ..:....|.|.|:..:
  Fly     8 LTFFLLPLLGSTQFLDMACGIRAHSPSVPRVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNR 72

Human    65 WVLSAAHCF--QNSYTIGLGLHSLEADQEPGSQ------------MVEASLSVRHPEYNRPLLAN 115
            .||:|||||  :......||    |.|:|....            |||...  ||..||...:|.
  Fly    73 LVLTAAHCFLDRTELVARLG----EYDREEYEMCHDSYCTYRIEAMVERGF--RHRHYNPMTMAY 131

Human   116 DLMLIKLDESVSESDTIRSISIA----------SQCPTAGNSCLVSGWGLLANGRMPTVLQCVNV 170
            |:.:::|...|..:|.||.|.|.          |..|..|     :|||...:......|:.|::
  Fly   132 DIAILRLYRKVQYTDNIRPICIVIDPRWRKYIDSLDPLTG-----TGWGKTESEGDSAKLRTVDL 191

Human   171 SVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP---LICNG----YLQ-GLVSFGKAP 227
            :....|||.:........:.|||  |.::.:.||||||||   ||..|    ::| |:.||....
  Fly   192 ARKHPEVCRRYATLSLTANQFCA--GNERSNLCNGDSGGPVGALIPYGKSKRFVQVGIASFTNTQ 254

Human   228 CGQVGVPGVYTNLCKFTEWI 247
            |..|   .|:|::..:.:||
  Fly   255 CVMV---SVFTDVMSYVDWI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	75/250 (30%)
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	73/249 (29%)