Protein Alignment ABCG1 and Abcg1

DIOPT Version :10

• Sequence 1: XP_024307909.1
• Gene: ABCG1 / 9619
• HGNCID: 73
• Length: 786
• Species: Homo sapiens
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 703
• Identity: 583/703 - (82%)
• Similarity: 603/703 - (85%)
• Gaps: 51/703 - (7%)

Human    88 GTATAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQG--KRVPMSGLQGSSIVIMPPSNR 150
            |||.......||:...| ...|.|.:.||..::.|....|.|  |:|..:..:....     |:.
Mouse    11 GTAMNASSYSAAMTEPK-SVCVSVDEVVSSNVDEVETDLLNGHLKKVDNNFTEAQRF-----SSL 69

Human   151 PLKASAASCTWSVQVQGGPHHLGVVAISGKVLSAAHGAGRAYGWGFPGDP--MEEGYKTLLKGIS 213
            |.:|:                   |.|..|.||          :..|..|  .::||||||||||
Mouse    70 PRRAA-------------------VNIEFKDLS----------YSVPEGPWWKKKGYKTLLKGIS 105

Human   214 GKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLP 278
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Mouse   106 GKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLP 170

Human   279 HLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNP 343
            |||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||
Mouse   171 HLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNP 235

Human   344 PVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGK 408
            ||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||
Mouse   236 PVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGK 300

Human   409 VCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNP 473
            |.||||||||||||||||||||||||||||||||||||||||||||||||:|:|||||||.:|||
Mouse   301 VSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDADYKRDLGGDTDVNP 365

Human   474 FLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSH 538
            ||||||:||            ||:|||||||||||||||||||||||||||||||||||||||||
Mouse   366 FLWHRPAEE------------DSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSH 418

Human   539 IGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL 603
            |||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||
Mouse   419 IGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSL 483

Human   604 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAAST 668
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   484 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAAST 548

Human   669 SLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDI 733
            ||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||
Mouse   549 SLQVATFVGPVTAIPVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDI 613

Human   734 DETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 786
            .||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   614 AETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCG1	XP_024307909.1	3a01204	202..786	CDD:273361	556/583 (95%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	566/651 (87%)