Protein Alignment CYTIP and Cytip

DIOPT Version :9

• Sequence 1: NP_004279.3
• Gene: CYTIP / 9595
• HGNCID: 9506
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_001012086.1
• Gene: Cytip / 311047
• RGDID: 1307990
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 360
• Identity: 294/360 - (81%)
• Similarity: 319/360 - (88%)
• Gaps: 2/360 - (0%)

Human     1 MSLQRLL-QHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRS 64
            ||||||| |.|||||| ::||..|||||.||||.||::||||||||||||||||||||||||.||
  Rat     1 MSLQRLLQQQSSNGNL-EYCADSAYSSYPTLTGPLTVEDNRRIQMLADTVATLPRGRKQLALARS 64

Human    65 SSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGD 129
            |||.|||.||||:||||||||.|||||||:||.||||.||||:.|:|||:||||||||||||.||
  Rat    65 SSLGDFSCSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAGLQVGD 129

Human   130 VLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRS 194
            :.||:|||||||||:||||||||||||||||||||||||.:|.|||||||.||||||:||||.||
  Rat   130 IFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKLQTLKQTLKKKWVELRS 194

Human   195 LQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSED 259
            |.|||.|||||||||.|:||||:|||.||||.|.||.||.:||.||||||||||||||:|:||||
  Rat   195 LHLQEQRLLHGDAANSPNLENMNLDESSLFGNLLGPSPAFLDRPRLSSESSCKSWLSSLTVDSED 259

Human   260 GYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSRRNRSISNTSSGSMSPLWEGNLSSM 324
            .|.|.|||||.|||||||||||||||..|:||:.||.:|||||||||.|||||.|||||.|.||:
  Rat   260 DYGTSVSEDSIRGAFSRQTSTDDECFHSKDGDEILRNASSRRNRSISITSSGSFSPLWESNYSSV 324

Human   325 FGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF 359
            |||||||||:||||||:||||||||||||||||||
  Rat   325 FGTLPRKSRRGSVRKQILKFIPGLHRAVEEEESRF 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYTIP	NP_004279.3	PDZ_signaling	76..161	CDD:238492	70/84 (83%)
		Interaction with CYTH1	166..188		17/21 (81%)
Cytip	NP_001012086.1	PDZ_signaling	76..161	CDD:238492	70/84 (83%)
		Interaction with CYTH1. /evidence=ECO:0000250	166..188		17/21 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83683141
Domainoid	1	1.000	316	1.000	Domainoid score	I14624
eggNOG	1	0.900	-	-		E1_KOG3528
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3167
Inparanoid	1	1.050	571	1.000	Inparanoid score	I10616
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG38844
OrthoDB	1	1.010	-	-		D133537at9347
OrthoFinder	1	1.000	-	-		FOG0003007
OrthoInspector	1	1.000	-	-		oto130309
orthoMCL	1	0.900	-	-		OOG6_118717
Panther	1	1.100	-	-	LDO	PTHR15963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X8399
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270