Protein Alignment CYTIP and gras-1

DIOPT Version :9

• Sequence 1: NP_004279.3
• Gene: CYTIP / 9595
• HGNCID: 9506
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_492164.1
• Gene: gras-1 / 172549
• WormBaseID: WBGene00009272
• Length: 245
• Species: Caenorhabditis elegans
• Alignment Length: 223
• Identity: 58/223 - (26%)
• Similarity: 95/223 - (42%)
• Gaps: 46/223 - (20%)

Human    23 AYSSYSTLTGSL---TMDDNRRIQ-MLADTVATLPRGRKQLALTRSSSLSDFSW-------SQRK 76
            |:|:.||.:.|.   |.|||...| :|.|.....|             |:|:.:       :||.
 Worm     6 AHSAVSTSSSSSKYDTPDDNISEQRLLCDAKEEYP-------------LNDYLFDGINQESAQRS 57

Human    77 LVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEG 141
            |:...:....:|||.:|||..:..::.|.|..|.:..:..||||...|:..||::..:|..|...
 Worm    58 LLLCRQTFETSFGFALQSYVFKRTSSNSYERITYVDYVSADSPADRCGITRGDMVIAVNEKSVVT 122

Human   142 FTYKQVVDLIRSSGNLLTIETLNGTMIL------KRTELEAKLQVLKQTLKQKWVEYRSLQLQEH 200
            .::.::|:.|        .:.|..:::|      :..||..:...|:..|..|..|.|.|:..|.
 Worm   123 ASHAEIVESI--------AQCLQVSLVLVFKDVARIVELSMRSIQLRFMLDAKIRELRMLEKTEE 179

Human   201 RLL------HGDAANCPSLEN--MDLDE 220
            .|.      ||:.....|||:  .:|||
 Worm   180 DLQALYDDEHGNEEEDESLESTLYELDE 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYTIP	NP_004279.3	PDZ_signaling	76..161	CDD:238492	21/84 (25%)
		Interaction with CYTH1	166..188		5/27 (19%)
gras-1	NP_492164.1	PDZ	67..145	CDD:238080	22/85 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161454151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15963
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840