Protein Alignment SOX13 and Sox15

DIOPT Version :9

• Sequence 1: NP_005677.2
• Gene: SOX13 / 9580
• HGNCID: 11192
• Length: 622
• Species: Homo sapiens
• Sequence 2: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 114/466 - (24%)
• Similarity: 170/466 - (36%)
• Gaps: 165/466 - (35%)

Human   288 EPS----QPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRD----------------- 331
            |||    .|.:|.....:.:.|:.|.:|....|:.... |.|||...|
  Fly     2 EPSYDHEHPHHLLTNYNSKKYPHVSRTPEYSHSTGSDY-PEHGGYLTDGRLMHESNSDAGIYHVR 65

Human   332 --LQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGA--------------------------L 368
              .:.|.|||....:.......:.:.:|....||||.:                          |
  Fly    66 QGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLL 130

Human   369 DGSPNTPFRKDLISLDSSP-------AKERLEDGCVH-PLEEA-MLSCDMDG----------SRH 414
            .|..|:...|.|    |.|       ...::||...| |:|.| |.|.|..|          .||
  Fly   131 GGGGNSVLNKFL----SHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERH 191

Human   415 FP--------------ESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSM 465
            .|              :|...|.|:|||||||||||.||:|:....||:||:.:||:||.:|:|:
  Fly   192 KPLPADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSL 256

Human   466 TNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVI 530
            |.|:::||.||..||...|:.::|:|||:||          |.:..:.:|:....::.:..|
  Fly   257 TPQDRRPYVEEAERLRVIHMTEHPNYKYRPR----------RRKQSKLRAMQPGGKEQSESS--- 308

Human   531 PPQAGQVQMSSSDVLYPRAAGMPLA--------------------------------QPLVEHYV 563
             |..|.....|:    |:.|..|||                                |||...|.
  Fly   309 -PNPGTGGSKSN----PKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYS 368

Human   564 PRSLD------------------PNMPVIVNTCSLREEGEGTDDR------HSVADGEMYRYSED 604
            |.|:|                  |  |.::|..|  ..|.|.|:.      ...:.....:..::
  Fly   369 PSSVDCYSNADSTEQIESLAANCP--PALLNESS--PTGGGYDNSLLLKKLTKPSPSRAAKSRQE 429

Human   605 EDSEGEEKSDG 615
            :.::.|||:.|
  Fly   430 KLAKSEEKNKG 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX13	NP_005677.2	SOX-TCF_HMG-box	423..494	CDD:238684	37/70 (53%)
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	37/70 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810