Protein Alignment GDF3 and scw

DIOPT Version :9

• Sequence 1: NP_065685.1
• Gene: GDF3 / 9573
• HGNCID: 4218
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 215
• Identity: 66/215 - (30%)
• Similarity: 92/215 - (42%)
• Gaps: 37/215 - (17%)

Human   176 QGAVHFNLLDVAKDWNDN---PRKNFGLFLEILVKEDRDSGVNFQPEDTCARL------RCSLHA 231
            :|.:.|||.|..:.|..|   .|:|          |.|.|..:.|.....|.|      |.||..
  Fly   195 RGWLEFNLTDTLRYWLHNKGLQRRN----------ELRISIGDSQLSTFAAGLVTPQASRTSLEP 249

Human   232 SLLVVTLNPDQC---------HPSRKRRAA---------IPVPKLSCKNLCHRHQLFINFRDLGW 278
            .::.....|:..         ....||||.         .||........|.|....::|::|..
  Fly   250 FIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHM 314

Human   279 HKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQD 343
            |.|:||||.|.|.:|.|.|.|.|...:|::|:|.:|.|||...|.:|:..|:||.|..|::|...
  Fly   315 HNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTVLGAITILRYL 379

Human   344 NNDNVILRHYEDMVVDECGC 363
            |.|.:.|..|:..|..||||
  Fly   380 NEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDF3	NP_065685.1	TGFb_propeptide	<109..220	CDD:279078	13/46 (28%)
		TGFB	264..364	CDD:214556	41/100 (41%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	18/68 (26%)
		TGFB	300..400	CDD:214556	41/100 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810