Protein Alignment GTPBP1 and gtpbp1

DIOPT Version :10

• Sequence 1: XP_016884589.1
• Gene: GTPBP1 / 9567
• HGNCID: 4669
• Length: 726
• Species: Homo sapiens
• Sequence 2: NP_001072172.1
• Gene: gtpbp1 / 594925
• XenbaseID: XB-GENE-951182
• Length: 666
• Species: Xenopus tropicalis
• Alignment Length: 673
• Identity: 565/673 - (83%)
• Similarity: 592/673 - (87%)
• Gaps: 39/673 - (5%)

Human     4 ERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEAL-NGEPELDLTSKLVL 67
            ||::|  |||||||||:|||.                |.|||||.|||.| |||.::||||||||
 Frog    10 ERNQS--DSPVPASMFSPEPD----------------GEDSDCSLDGEPLRNGEADIDLTSKLVL 56

Human    68 VSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVI 132
            |||::|||||||||:.:|||||.||||||||||||||||||:|||||||.|||.||||||.||:|
 Frog    57 VSPSAEQYDSLLRQLRDRMDEGRGETIYVIGQGSDGTEYGLNEADMEASVATVTSMAEQIIADMI 121

Human   133 LLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLF 197
            ||||.|||||:||||||||.|||||||||||||||||||||||||||||||||||||||||||||
 Frog   122 LLREHQEAGGKVRDYLVRKSVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLF 186

Human   198 RHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKT 262
            |||||||||||||||||||||||.|.|||||||||||||||||||||:|:|||||||||||||||
 Frog   187 RHKHEIESGRTSSVGNDILGFDSHGQVVNKPDSHGGSLEWTKICEKSSKIITFIDLAGHEKYLKT 251

Human   263 TVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQR 327
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   252 TVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQR 316

Human   328 LLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREE 392
            |||||||||||||||:|||||||||||||||||||||||||||||::||||||||||||:|.|||
 Frog   317 LLKSPGCRKIPVLVQNKDDVIVTASNFSSERMCPIFQISNVTGENMELLKMFLNLLSPRSSSREE 381

Human   393 EPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRG 457
            |||||||||||||||||||||||||||||||||.|||||||||||.|||||||||||||||||||
 Frog   382 EPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDLLLLGPDPLGNFTSIAVKSIHRKRMPVKEVRG 446

Human   458 GQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTA 522
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   447 GQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTA 511

Human   523 TILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQ 587
            |||||.:||||||||||||||||||||||||||||||||||||||||||||||:|||.|||||||
 Frog   512 TILSMSRDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQSTNNLPMNSKPQ 576

Human   588 QIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQ------------- 639
            |:|||||||.|..|:||..|      ||..|.:.:.|...|..|.:.:||.|
 Frog   577 QVKMQSTKKSPHGKKDEQIP------GAAVPEEASPSAAVGVTAGAGSLQAQTASAEDFQCRAEN 635

Human   640 -PKPSSGGRRRGGQRHKSQVQGA 661
             ||...|||||||||||.:.|||
 Frog   636 KPKTGGGGRRRGGQRHKVKSQGA 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTPBP1	XP_016884589.1	GTPBP1	77..574	CDD:444076	471/496 (95%)
gtpbp1	NP_001072172.1	GTPBP1	66..563	CDD:444076	471/496 (95%)
		GTPBP1_like	151..375	CDD:206728	216/223 (97%)