Protein Alignment GTPBP1 and gtpbp1

DIOPT Version :10

• Sequence 1: XP_016884589.1
• Gene: GTPBP1 / 9567
• HGNCID: 4669
• Length: 726
• Species: Homo sapiens
• Sequence 2: XP_005164056.1
• Gene: gtpbp1 / 378721
• ZFINID: ZDB-GENE-030909-12
• Length: 670
• Species: Danio rerio
• Alignment Length: 680
• Identity: 535/680 - (78%)
• Similarity: 575/680 - (84%)
• Gaps: 41/680 - (6%)

Human    11 DSPVPASMFAPEPSSPGAARAAAAAARLHGGFD-SDCSEDGEALNGEP---ELDLTSKLVLVSPT 71
            :|.||||||||              .|..|..| |||.:||:..|||.   .:|.:|||.||||.
Zfish    20 ESVVPASMFAP--------------GRGCGDDDESDCFDDGDMFNGETVDLGIDFSSKLALVSPN 70

Human    72 SEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRE 136
            .||||.||||:.|||||||||||||:|.||||.:|||:|:||:||.|||:||.||||||:|||||
Zfish    71 GEQYDLLLRQLRERMDEGCGETIYVLGVGSDGGDYGLNESDMQASVATVRSMCEQIEADLILLRE 135

Human   137 RQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKH 201
            |.||||:|||||:|:|||:.|||||||||||||||||||||||||||||||||||||||||||||
Zfish   136 RTEAGGQVRDYLIRRRVGEADFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKH 200

Human   202 EIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFG 266
            |:||||||||||||||||.||.||||||||||||:||||||||:|||||||||||||||||||||
Zfish   201 EMESGRTSSVGNDILGFDQEGQVVNKPDSHGGSLDWTKICEKSSKVITFIDLAGHEKYLKTTVFG 265

Human   267 MTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKS 331
            ||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||::|||
Zfish   266 MTGHLPDFCMLMIGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQKILKS 330

Human   332 PGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAE 396
            |||||||||||:|||||||||||||||:|||||||||||||:|||||||||||.|:|:::.||||
Zfish   331 PGCRKIPVLVQNKDDVIVTASNFSSERICPIFQISNVTGENMDLLKMFLNLLSSRSSFKDHEPAE 395

Human   397 FQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTA 461
            |||||||||||||||||||||||||:|||||||||||||.||||.||||||||||||||||||||
Zfish   396 FQIDDTYSVPGVGTVVSGTTLRGLIRLNDTLLLGPDPLGAFLSITVKSIHRKRMPVKEVRGGQTA 460

Human   462 SFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILS 526
            |||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||
Zfish   461 SFALKKIKRSSIRKGMVMVSPRLNPQAYWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILS 525

Human   527 MDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKM 591
            |.:|||||||||||||||||||||||.|||||||||||||||||||||.:|||.|.||||.||||
Zfish   526 MTRDCLRTGDKATVHFRFIKTPEYLHTDQRLVFREGRTKAVGTITKLLLSTNNQPSNSKPPQIKM 590

Human   592 QSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQP-----KPSSGGRRRGG 651
            |||||.|..:.|.|.||...||...||       .|......:.::..|     ||.||||||||
Zfish   591 QSTKKTPARREDGGAPSSEEAVSTAPP-------AAQNTPQQTEMEEDPQNKENKPKSGGRRRGG 648

Human   652 QRHKSQVQGANSEFPWRRITALQVDVAGRV 681
            ||||.:.| :||          .|.:||.|
Zfish   649 QRHKGKPQ-SNS----------TVTLAGAV 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTPBP1	XP_016884589.1	GTPBP1	77..574	CDD:444076	452/496 (91%)
gtpbp1	XP_005164056.1	GTPBP1	77..573	CDD:444076	452/495 (91%)