DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MACROH2A1 and His2A:CG33832

DIOPT Version :9

Sequence 1:	NP_613258.2	Gene:	MACROH2A1 / 9555	HGNCID:	4740	Length:	372	Species:	Homo sapiens
Sequence 2:	NP_001027331.1	Gene:	His2A:CG33832 / 3772632	FlyBaseID:	FBgn0053832	Length:	124	Species:	Drosophila melanogaster

Alignment Length:	123	Identity:	79/123 - (64%)
Similarity:	93/123 - (75%)	Gaps:	2/123 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     1 MSSR--GGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILEL 63
            ||.|  |||.|....|||.:||:.|||||:.|.::||:...|:|.|||||:|||:|||.||:|||
  Fly     1 MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLEL 65

Human    64 AGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSK 121
            ||||||||||.|:.|||:.||:.||||||:||.|||||.|||||||...||.||...|
  Fly    66 AGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKK 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MACROH2A1	NP_613258.2	H2A	5..117	CDD:238029	73/111 (66%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..180
		Macro_H2A-like	178..368	CDD:394875
His2A:CG33832	NP_001027331.1	PTZ00017	16..124	CDD:185399	72/108 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5262
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810