DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1E1 and GstE11

DIOPT Version :9

Sequence 1:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens
Sequence 2:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	39/183 - (21%)
Similarity:	68/183 - (37%)	Gaps:	38/183 - (20%)

- Green bases have known domain annotations that are detailed below.

Human     2 AAAAELSLLEKSLGLSKGNKYSAQ-----GERQIPVLQTNNGPSLTGLTTIAAHLVKQ---ANKE 58
            |||..|.|..:.:.:..|...||:     .:..||||. :||..::....|.::|..:   ...:
  Fly    23 AAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLD-DNGTIVSDSHIICSYLADKYAPEGDD 86

Human    59 YLLGSTAEEKAIVQQWLEY-------RVTQV--------DGHSSKNDIHTLLK---DLNSYLEDK 105
            .|.....|::.:|...|.|       |:..:        .|....:.:..|.|   .|...|.:.
  Fly    87 SLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDRVAYLQKAYDGLEHCLAEG 151

Human   106 VYLTGYNFTLADILLYYGLHRFIVDLTVQ-----EKEKYLNVSRWFCHIQHYP 153
            .||.|...|:||:.....:.      |.:     |.:::..:.:|...||..|
  Fly   152 DYLVGDKLTIADLSCIASVS------TAEAFAPIEPDQFPRLVQWVKRIQALP 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1E1	NP_004271.1	N-terminal	2..56		16/61 (26%)
		Linker	57..63		1/5 (20%)
		C-terminal	64..152		21/110 (19%)
		GST_C_AIMP3	65..165	CDD:198338	22/112 (20%)
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	38/181 (21%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	16/55 (29%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	22/111 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810