DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment EEF1E1 and GstE5

DIOPT Version :9

Sequence 1:NP_004271.1 Gene:EEF1E1 / 9521 HGNCID:3212 Length:174 Species:Homo sapiens
Sequence 2:NP_611327.1 Gene:GstE5 / 37110 FlyBaseID:FBgn0063495 Length:222 Species:Drosophila melanogaster


Alignment Length:147 Identity:30/147 - (20%)
Similarity:61/147 - (41%) Gaps:22/147 - (14%)


- Green bases have known domain annotations that are detailed below.


Human    27 ERQIPVLQTNNGPSLTGLTTIAAHLV-KQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSK-- 88
            |..:|.|: ::|..:.....|.|:|| |.|:.:.|......::|:|.|.|.:....|..:..|  
  Fly    52 EHTVPTLE-DDGNYIWDSHAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAI 115

Human    89 ------NDIHTLLKD-----------LNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEK 136
                  |.::.:.|:           :.::|....|:.|...|:||..|...:...:..:.: ::
  Fly   116 TKPLFFNGLNRIPKERYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEI-DR 179

Human   137 EKYLNVSRWFCHIQHYP 153
            .||..:..|...::..|
  Fly   180 LKYPRIIEWVRRLEKLP 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EEF1E1NP_004271.1 N-terminal 2..56 9/29 (31%)
Linker 57..63 1/5 (20%)
C-terminal 64..152 18/106 (17%)
GST_C_AIMP3 65..165 CDD:198338 19/108 (18%)
GstE5NP_611327.1 GstA 4..196 CDD:223698 29/145 (20%)
Thioredoxin_like 4..77 CDD:294274 7/25 (28%)
GST_C_Delta_Epsilon 91..209 CDD:198287 19/107 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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