Protein Alignment SPTLC2 and Sptlc2

DIOPT Version :10

• Sequence 1: NP_004854.1
• Gene: SPTLC2 / 9517
• HGNCID: 11278
• Length: 562
• Species: Homo sapiens
• Sequence 2: NP_001032174.1
• Gene: Sptlc2 / 366697
• RGDID: 1305447
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 536/562 - (95%)
• Similarity: 552/562 - (98%)
• Gaps: 2/562 - (0%)

Human     1 MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEAFEE 65
            ||||||||||||.:||||||.||||||||:|||  .|..||||||||:|:|||||||||||||||
  Rat     1 MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRSS--TATIAAAGQIHHITENGGLYKRPFNEAFEE 63

Human    66 TPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRI 130
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat    64 TPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRI 128

Human   131 RDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKV 195
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||:|
  Rat   129 RDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEV 193

Human   196 LEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDE 260
            |:.||||||||||||||||||||||:|||||||||||:.||||||||||||||||||||||||||
  Rat   194 LKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDE 258

Human   261 LNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIV 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   259 LNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIV 323

Human   326 RLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGG 390
            |||||||||||||||||||||||||||||:|||||:|||||||||||||||||||||||||||||
  Rat   324 RLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGG 388

Human   391 KKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKE 455
            ||||||||||||||||||||:||||:||||||||||||||||||||||:||||||||||||||||
  Rat   389 KKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKE 453

Human   456 MGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEI 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   454 MGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEI 518

Human   521 LDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED 562
            |||||||||||||||||||||||.:|||||||||||||||||
  Rat   519 LDTALKEIDEVGDLLQLKYSRHRPLPLLDRPFDETTYEETED 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPTLC2	NP_004854.1	AAT_I	67..542	CDD:450240	461/474 (97%)
Sptlc2	NP_001032174.1	AAT_I	65..542	CDD:450240	463/476 (97%)