Protein Alignment SPTLC2 and Sptlc2

DIOPT Version :10

• Sequence 1: NP_004854.1
• Gene: SPTLC2 / 9517
• HGNCID: 11278
• Length: 562
• Species: Homo sapiens
• Sequence 2: NP_035609.1
• Gene: Sptlc2 / 20773
• MGIID: 108074
• Length: 560
• Species: Mus musculus
• Alignment Length: 562
• Identity: 540/562 - (96%)
• Similarity: 554/562 - (98%)
• Gaps: 2/562 - (0%)

Human     1 MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEAFEE 65
            ||||||||||||.:||||||.||||||||:|||  .|..||||||||||:|||||||||||||||
Mouse     1 MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRSS--TATVAAAGQIHHVTENGGLYKRPFNEAFEE 63

Human    66 TPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRI 130
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
Mouse    64 TPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRI 128

Human   131 RDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKV 195
            ||||||||||||||:||||||:|||||||||||||||||||||||||||||||||||||||||:|
Mouse   129 RDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEV 193

Human   196 LEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDE 260
            |:|||||||||||||||||||||||:||||||||||||.||||||||||||||||||||||||||
Mouse   194 LKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDE 258

Human   261 LNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIV 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   259 LNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIV 323

Human   326 RLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGG 390
            |||||||||||||||||||||||||||||:|||||:|||||||||||||||||||||||||||||
Mouse   324 RLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGG 388

Human   391 KKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKE 455
            ||||||||||||||||||||:||||:||||||||||||||||||||||:||||||||||||||||
Mouse   389 KKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKE 453

Human   456 MGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEI 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   454 MGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEI 518

Human   521 LDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED 562
            ||||||||||||||||||||||||||||||||||||||||||
Mouse   519 LDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPTLC2	NP_004854.1	AAT_I	67..542	CDD:450240	462/474 (97%)
Sptlc2	NP_035609.1	AAT_I	65..540	CDD:450240	462/474 (97%)