Sequence 1: | NP_008919.3 | Gene: | ADAMTS1 / 9510 | HGNCID: | 217 | Length: | 967 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_572247.2 | Gene: | AdamTS-B / 31490 | FlyBaseID: | FBgn0029791 | Length: | 1023 | Species: | Drosophila melanogaster |
Alignment Length: | 1053 | Identity: | 346/1053 - (32%) |
---|---|---|---|
Similarity: | 485/1053 - (46%) | Gaps: | 195/1053 - (18%) |
- Green bases have known domain annotations that are detailed below.
Human 37 LLLAAALLAVSDALG-RP-----SEE----DEELVVP------------ELERA----------- 68
Human 69 ----PGHGTTRLRLHAF----DQQLDLELRPDSSFLAPGFTLQNVGRKSGSETPLPETDLAHCFY 125
Human 126 SGTVNGDPSSAAALSLCEGVRGAFYLLGEAYFIQPLPAASERLATAAPGEKPPAPLQFH------ 184
Human 185 ---------LLRRN--RQGDVGGT------CGVVDDEPRPTGKAETEDEDEGTEGEDEGAQ---- 228
Human 229 ------------WSPQDPALQGV------------GQPTGTGSIRKKRFVSSHRYVETMLVADQS 269
Human 270 MAEFHGSGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQKGPE--VTSNAALTLRNF 332
Human 333 CNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAF 397
Human 398 TTAHELGHVFNMPHDDAK-QCASLNGVNQDSHMMASMLSNLDHSQPWSPCSAYMITSFLDNGHGE 461
Human 462 CLMDKPQNPI---QLPGDLPGTSYDANRQC--QFTFGEDSK--HCPDAASTCSTLWCTGTSGGVL 519
Human 520 VCQTKHFPWADGTSCGEGKWCINGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMR 584
Human 585 ECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 649
Human 650 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKC 714
Human 715 GVCGGNGSTCKKISGSVT---SAKPG-YHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG 775
Human 776 --TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSF------SPLKEPLTIQVLTVGNAL 832
Human 833 RPKIKYTYFVKKKKESFNAIPTFSA-------WVIEEWGECSKSCELGWQRRLVECRDINGQ--- 887
Human 888 ---PASECAKEVKPA-STRPCADHPCP-QWQLGEWSSCSKTCGK-GY-----KKRSLKCLSHDGG 941
Human 942 VLSHESCDPLKKP 954 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ADAMTS1 | NP_008919.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..27 | ||
Pep_M12B_propep | 66..166 | CDD:279848 | 34/118 (29%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 192..250 | 13/91 (14%) | |||
Cysteine switch. /evidence=ECO:0000250 | 196..203 | 3/12 (25%) | |||
Reprolysin | 258..467 | CDD:279729 | 94/211 (45%) | ||
ZnMc_ADAMTS_like | 258..463 | CDD:239801 | 91/207 (44%) | ||
ADAM_CR | 468..548 | CDD:301627 | 37/86 (43%) | ||
TSP1 | 562..614 | CDD:214559 | 29/51 (57%) | ||
Spacer | 725..849 | 30/135 (22%) | |||
ADAM_spacer1 | 725..842 | CDD:283607 | 30/128 (23%) | ||
TSP1 | 858..910 | CDD:214559 | 21/58 (36%) | ||
TSP1 | 912..967 | CDD:214559 | 16/49 (33%) | ||
AdamTS-B | NP_572247.2 | Pep_M12B_propep | 78..194 | CDD:279848 | 36/128 (28%) |
ZnMc_ADAMTS_like | 314..518 | CDD:239801 | 92/208 (44%) | ||
Reprolysin | 315..521 | CDD:279729 | 93/210 (44%) | ||
ADAM_CR | <558..602 | CDD:301627 | 22/47 (47%) | ||
TSP1 | 614..666 | CDD:214559 | 29/51 (57%) | ||
ADAM_spacer1 | 773..886 | CDD:283607 | 30/135 (22%) | ||
TSP1 | 901..956 | CDD:214559 | 20/55 (36%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3538 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5862 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D125522at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100241 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
5 | 4.670 |