Protein Alignment SCARB2 and CG10345

DIOPT Version :9

• Sequence 1: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_650563.2
• Gene: CG10345 / 42017
• FlyBaseID: FBgn0027562
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 439
• Identity: 121/439 - (27%)
• Similarity: 206/439 - (46%)
• Gaps: 37/439 - (8%)

Human     9 AGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPE 73
            :..|.:.||.....::::...|..:|..:.    |:.||.....|..|||.||...|.||.||.:
  Fly    17 SAALGMTLLFFGSLVIISDPLQSILDTQLS----LKPGTLLHRLWLLPPLDVYINVYMFNYTNVD 77

Human    74 EILRGETPR--VEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTL 136
            |...|...:  ::|||||.|:|:.:..|:.:.::..||:....:.|||..::||||||||.||..
  Fly    78 EFTSGRASKLQLQEVGPYVYKEVLSNHNVTYNESNNTITYSPKREYVFAPERSVGDPKIDRIRAP 142

Human   137 NIPVL--TVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRP---DIS 196
            |||::  |.:..|...|....:.|:.:....:..:..:|.:.:|||:|.::.|...|.|   |.|
  Fly   143 NIPLMGVTTLASSLSMFAALGLSAITRQLNSQPMLEMSVHDYMWGYEDHLVELASRFVPNWIDFS 207

Human   197 PYFG----LFYEKNGTNDGDYVFLTGEDSY-LNFT------KIVEWNGKTSLDWWITDK------ 244
            . ||    ||.|.|.:|..:......:|.| :..|      .:...||:.....|..::
  Fly   208 S-FGIMEKLFREGNESNVFNMNLPEPKDKYGMRMTDAPRGYTVDSINGERGFKGWQYNEETNGTM 271

Human   245 CNMINGTDGDSFHPL-ITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDN 308
            ||.|.|:...:..|| :.:::..:::...|||.:.:.|:...:..||.||.:.:..:...:..||
  Fly   272 CNRIWGSHDATLFPLDMDENDEFFLYRRTFCRRLPVKFNRTTTFNGLDAFEFVMEPDSFDSEVDN 336

Human   309 AG---FCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPN-QEDHETFVDI 369
            |.   :| ....||..||.|||.|....|:.:::|||..||...:...:|:.|| .....||| :
  Fly   337 ANSSCYC-KNNRCLKKGVGNVSPCYYNIPLAITYPHFMHADPSLLEPFDGLQPNVSRFTSTFV-V 399

Human   370 NPLTGIILKAAK-RFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHI 417
            .|..|..::... |.|.|..|.|::..........|:.|:::::.::.:
  Fly   400 QPQLGAPMQGTHLRLQANQVVGKVNFNRMMTPFENMILPLLWVDLNIDV 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	118/420 (28%)
		Important for interaction with GBA	155..191		7/35 (20%)
CG10345	NP_650563.2	CD36	21..488	CDD:279474	120/435 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920