Protein Alignment SCARB2 and CG40006

DIOPT Version :9

• Sequence 1: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_001036401.1
• Gene: CG40006 / 3355123
• FlyBaseID: FBgn0058006
• Length: 689
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 123/458 - (26%)
• Similarity: 215/458 - (46%)
• Gaps: 36/458 - (7%)

Human    12 LSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEIL 76
            :..|.::||..:.|...:    |...:.|:::..|.|.|:.|.:||:.:|.:.|.||:||....|
  Fly    97 IGFLAIITSTLIKVLEPY----DLIFKWKLIMTEGGEIFNLWAQPPVDLYIKIYLFNITNANAFL 157

Human    77 RG-ETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPV 140
            .| |..|||:||||.|:|:....|:.|..| .|:|:..:...|::.:.|....:.|.:..|||.:
  Fly   158 AGREQLRVEQVGPYVYKEIMTHENVTFNSN-NTMSSTPSHPLVWQEEMSGNCREDDEVVMLNIAM 221

Human   141 LTV--IEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFY 203
            |.:  :..:|...:|..::.:|.:.:.:..|..|..|.::||...:.:|.:.|.|:     .:.:
  Fly   222 LAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFGYPSALATLGNTFLPN-----WISF 281

Human   204 EKNGTNDGDYVFLTGEDSYLNFTKI---------VEWNGKTSLDWWITDKCNMIN-GTDGDSFHP 258
            ||.|..|..|.|.|..:::  :|.:         ..:.|:|:|..|..|.|:.|. .:||..|..
  Fly   282 EKVGLIDRMYDFSTDFETF--YTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDGTKFKS 344

Human   259 LITKDEVLYVFPSDFCRSVYITFSDYESVQG-LPAFRYKVPAEILANTSDNAG---FCIPEGNCL 319
            .|..:|.:..|....||.:.:.....|...| |..:.|........|.:.|..   || .:|:|.
  Fly   345 FIQPNETVKFFRKSMCRPINLYRVGNEKTYGSLKGYNYVFEDNAFDNGATNEANKCFC-RKGDCQ 408

Human   320 GSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQ 384
            ..|:::|:.|..|.||.:|||||...|......:.|:.|:.:.|.:...|.|.:|:.|..:.:.|
  Fly   409 PVGLIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGLPLSLSVKVQ 473

Human   385 INIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFF 449
            ||::.|.|.:|........:..|:::.  .:.:.|...| |.|..|..|   ||..::..||.:.
  Fly   474 INMHFKDLSNFPVVSVFNHLTVPMLWF--EIMMSKLPDS-LDSRFNFYL---NILPLVNPLGFWS 532

Human   450 GLV 452
            |::
  Fly   533 GIL 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	119/442 (27%)
		Important for interaction with GBA	155..191		7/35 (20%)
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	123/458 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920