Protein Alignment TBX4 and tbx-37

DIOPT Version :9

• Sequence 1: XP_011523792.1
• Gene: TBX4 / 9496
• HGNCID: 11603
• Length: 609
• Species: Homo sapiens
• Sequence 2: NP_499444.2
• Gene: tbx-37 / 189977
• WormBaseID: WBGene00006556
• Length: 313
• Species: Caenorhabditis elegans
• Alignment Length: 271
• Identity: 90/271 - (33%)
• Similarity: 128/271 - (47%)
• Gaps: 32/271 - (11%)

Human   130 IKVGLHEKELWKKFHEAGTEMIIT-KAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFC 193
            |:|.|::.|:|:||:.. ||||:| |.||.:||.....|.|::|.:.|.:.|.:...|..:|||.
 Worm    10 IEVSLNKPEIWEKFYPK-TEMIVTRKRGRVIFPHLDYNVKGLDPDSLYSIYIHLERVDGIKYKFD 73

Human   194 DNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH----IILNSMHK 254
            ..:|..|||.:|.:|.:...||....||..||.:.|||..||:||   ||...    |:..|:||
 Worm    74 AGEWKEAGKGDPILPIQYKEHPRGKRTGTEWMSEPVSFAHLKITN---DPENKDQKLILAQSLHK 135

Human   255 YQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSD 319
            |.|.|||.:.|........:..........|.||.||:|||.::|:||:.:|.||.|||.:....
 Worm   136 YIPVLHIKQLDPYKGTFQMDFHGVEFRLEATQFIVVTAYQNEELTKLKVHHNKFASGFRSNGKRR 200

Human   320 LRVARLQSKEYPVISKSIMRQRLISPQLS------------------ATPDV-GPLLGTHQA-LQ 364
            |......|:..|....:.....|..|.:|                  :||.. .|....|.| .|
 Worm   201 LSSESENSENSPPKRSASAISSLTPPAISPPMDYTQQNPYFFNQNFFSTPQSHQPQFAAHSANAQ 265

Human   365 HYQH---ENGA 372
            :|.:   :|||
 Worm   266 NYNNFGAQNGA 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX4	XP_011523792.1	TBOX	129..318	CDD:238106	74/192 (39%)
tbx-37	NP_499444.2	TBOX	9..199	CDD:238106	74/192 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161449202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840