Protein Alignment SCARB1 and CG10345

DIOPT Version :10

• Sequence 1: NP_001354910.1
• Gene: SCARB1 / 949
• HGNCID: 1664
• Length: 552
• Species: Homo sapiens
• Sequence 2: NP_650563.2
• Gene: CG10345 / 42017
• FlyBaseID: FBgn0027562
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 143/525 - (27%)
• Similarity: 232/525 - (44%)
• Gaps: 83/525 - (15%)

Human    11 AGALGVAGLLCAVLGAVMIVMVP--SLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVM 73
            :.|||:..|.   .|:::|:..|  |::..|    :.:.|.:|...:|...|:..|::||.|:..
  Fly    17 SAALGMTLLF---FGSLVIISDPLQSILDTQ----LSLKPGTLLHRLWLLPPLDVYINVYMFNYT 74

Human    74 NPSEILKG--EKPQVRERGPYVYREFRHKSNITFN-NNDTVSFLEYRTFQFQPSKSHGS-ESDYI 134
            |..|...|  .|.|::|.|||||:|.....|:|:| :|:|:::...|.:.|.|.:|.|. :.|.|
  Fly    75 NVDEFTSGRASKLQLQEVGPYVYKEVLSNHNVTYNESNNTITYSPKREYVFAPERSVGDPKIDRI 139

Human   135 VMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMF 199
            ..|||.::|...:..:..|...|.::.....|..:..:..:|.:.||||:|.||.|.:::.|...
  Fly   140 RAPNIPLMGVTTLASSLSMFAALGLSAITRQLNSQPMLEMSVHDYMWGYEDHLVELASRFVPNWI 204

Human   200 PFKDKFGLFAEL--NNSDSGLFTVFT-------GVQ--NISRIHLVDKWNGLSKVDFWHSDQ--- 250
            .| ..||:..:|  ..::|.:|.:..       |::  :..|.:.||..||......|..::
  Fly   205 DF-SSFGIMEKLFREGNESNVFNMNLPEPKDKYGMRMTDAPRGYTVDSINGERGFKGWQYNEETN 268

Human   251 ---CNMINGT-SGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLF--- 308
               ||.|.|: ...::|..|........|....||.:.:.:..:..|.|:..:.||.....|
  Fly   269 GTMCNRIWGSHDATLFPLDMDENDEFFLYRRTFCRRLPVKFNRTTTFNGLDAFEFVMEPDSFDSE 333

Human   309 ---ANGSIYPPNEGFCPCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSL 370
               ||.|.|..|.   .||:.|:.|||.|.::.||.:::|||::|||.|.|...||.||....:.
  Fly   334 VDNANSSCYCKNN---RCLKKGVGNVSPCYYNIPLAITYPHFMHADPSLLEPFDGLQPNVSRFTS 395

Human   371 FLDIHPVTGIPM-NCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQL 434
            ...:.|..|.|| ...::||.:..:..|.........|.::|||||.         .|:.....|
  Fly   396 TFVVQPQLGAPMQGTHLRLQANQVVGKVNFNRMMTPFENMILPLLWV---------DLNIDVLCL 451

Human   435 VLMPKVMHYAQ--YVLL----ALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRT 493
            .|. .::|..:  :.||    |||.:|..|..:|                |..|.|:
  Fly   452 TLR-LLIHGIKWGFPLLQWSAALGMLLAGVYQLC----------------SALLLCF-------- 491

Human   494 LWPTA 498
             ||||
  Fly   492 -WPTA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCARB1	NP_001354910.1	CD36	16..446	CDD:460076	125/462 (27%)
CG10345	NP_650563.2	CD36	19..490	CDD:460076	138/507 (27%)