Protein Alignment MED20 and MED20

DIOPT Version :9

• Sequence 1: NP_004266.2
• Gene: MED20 / 9477
• HGNCID: 16840
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_001260223.1
• Gene: MED20 / 43952
• FlyBaseID: FBgn0013531
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 85/221 - (38%)
• Similarity: 130/221 - (58%)
• Gaps: 21/221 - (9%)

Human     1 MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYV 65
            ||||.:...|:.||||....::.|:::|..|||...|.|.|||||:  .::.....|..|:.::|
  Fly     1 MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETF--ISTPQPHNGAPGRAVHV 63

Human    66 MHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKV 126
            :||||||.|.|::.:||.    .::||..||:||:|:...|.|.|.:|||:||.|::|.||::|:
  Fly    64 LHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKL 128

Human   127 GTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLG-SHTPGAPAVFG------------- 177
            |:|||....:||.:|:||..||:.:.||.::.|.||.||| :.....|:.|.
  Fly   129 GSVTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQL 193

Human   178 -NRHDAVYGPADTMVQYMELFNKIRK 202
             .:|:.::.|.||:.||:|.|...||
  Fly   194 HAKHNDIFEPMDTVKQYLEQFTNYRK 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED20	NP_004266.2	Med20	1..198	CDD:400779	82/215 (38%)
MED20	NP_001260223.1	Med20	1..215	CDD:285776	85/221 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146976
Domainoid	1	1.000	157	1.000	Domainoid score	I4171
eggNOG	1	0.900	-	-		E1_KOG4309
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3158
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4241
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1112080at2759
OrthoFinder	1	1.000	-	-		FOG0007370
OrthoInspector	1	1.000	-	-		oto91795
orthoMCL	1	0.900	-	-		OOG6_104763
Panther	1	1.100	-	-	LDO	PTHR12465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.760