DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HAND2 and l(1)sc

DIOPT Version :9

Sequence 1:NP_068808.1 Gene:HAND2 / 9464 HGNCID:4808 Length:217 Species:Homo sapiens
Sequence 2:NP_476623.1 Gene:l(1)sc / 30983 FlyBaseID:FBgn0002561 Length:257 Species:Drosophila melanogaster


Alignment Length:91 Identity:31/91 - (34%)
Similarity:44/91 - (48%) Gaps:21/91 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    79 HYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADT---------- 133
            :|..:|.|...|.      |.||   |.:||.|.:.:|:.|..||:.:|....::          
  Fly    72 NYNNMPYGEQLPS------VARR---NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSK 127

Human   134 KLSKIKTLRLATSYIAYLMDLLAKDD 159
            ||||:.|||:|..||..|.|:|  ||
  Fly   128 KLSKVDTLRIAVEYIRGLQDML--DD 151

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HAND2NP_068808.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 76..116 11/36 (31%)
bHLH_TS_HAND2 100..161 CDD:381477 26/70 (37%)
l(1)scNP_476623.1 HLH <96..146 CDD:278439 15/49 (31%)
Peptidase_C11 <128..218 CDD:304483 15/26 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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