DRSC/TRiP Functional Genomics Resources

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Protein Alignment FHL5 and pk

DIOPT Version :9

Sequence 1:NP_001164278.1 Gene:FHL5 / 9457 HGNCID:17371 Length:284 Species:Homo sapiens
Sequence 2:NP_724538.1 Gene:pk / 45343 FlyBaseID:FBgn0003090 Length:1299 Species:Drosophila melanogaster


Alignment Length:254 Identity:66/254 - (25%)
Similarity:100/254 - (39%) Gaps:49/254 - (19%)


- Green bases have known domain annotations that are detailed below.


Human     9 QYCTASLLGKKYVLKDDSPYCVTCYD------RVFSNY-------------------CEECKKPI 48
            ||....||.:.....::..||.:..|      |:||..                   |:.|...|
  Fly   567 QYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDALGRGNVRQL
MSARPCDGCDDLI 631

Human    49 ESDSKDLCY------KDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKR 107
            .:.  |:..      .:..||..||.|:.|...||:..:..:|.|:.|...::.....:|..|..
  Fly   632 STG--DIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHA
ETLKPRCSACDE 694

Human   108 TIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI-- 170
            .|: .....|.:|..||...|.|..|.:.:|.:..|.:|...||:.||:..||.||::|.:.|  
  Fly   695 IIL-ADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFD
AMFAEYCDYCGEAIGV 758

Human   171 TSGGITFCDQLWH--KECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSK 227
            ..|.::...|.||  .|||.|:.||..|....|:.|....:|           .:||||
  Fly   759 DQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYC-----------SIACS
K 806

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FHL5NP_001164278.1 LIM <5..34 CDD:351770 6/24 (25%)
LIM1_FHL 37..95 CDD:188729 17/82 (21%)
LIM2_FHL5 102..155 CDD:188812 15/52 (29%)
LIM3_FHL 163..214 CDD:188732 17/54 (31%)
LIM4_FHL 222..277 CDD:188733 4/6 (67%)
pkNP_724538.1 PET_Prickle 523..618 CDD:193602 10/50 (20%)
LIM1_Prickle 624..682 CDD:188799 15/59 (25%)
LIM2_Prickle 687..742 CDD:188802 16/55 (29%)
LIM3_Prickle 747..805 CDD:188804 19/68 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1704
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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