Protein Alignment HOMER1 and Homer1

DIOPT Version :10

• Sequence 1: NP_004263.1
• Gene: HOMER1 / 9456
• HGNCID: 17512
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_113895.1
• Gene: Homer1 / 29546
• RGDID: 628725
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 345/366 - (94%)
• Similarity: 353/366 - (96%)
• Gaps: 12/366 - (3%)

Human     1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNM 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNM 65

Human    66 TFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQE 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 TFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQE 130

Human   131 SAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSH------------SSAISKHW 183
            ||||||||||||||||||||||||||||||||||||.||||||||            ||||||||
  Rat   131 SAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPAQNALPFSHSAGDRTQGLSHASSAISKHW 195

Human   184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTE 248
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
  Rat   196 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTE 260

Human   249 LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLE 313
            |:||:||||||||:||||||||||||||||||||||||||||||||||||||||||||:||||||
  Rat   261 LSQTVQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSELEQRLE 325

Human   314 KSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
            |||:||:|||:||||||||||||||||||||||||||||||
  Rat   326 KSQSEQDAFRSNLKTLLEILDGKIFELTELRDNLAKLLECS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER1	NP_004263.1	EVH1_Homer_Vesl	3..111	CDD:269917	107/107 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..173		57/58 (98%)
		Smc	<181..>352	CDD:440809	162/170 (95%)
		Required for tetramerization. /evidence=ECO:0000250|UniProtKB:Q9Z214	290..354		59/63 (94%)
Homer1	NP_113895.1	EVH1_Homer_Vesl	3..111	CDD:269917	107/107 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..189		61/74 (82%)
		Smc	<197..>364	CDD:440809	158/166 (95%)
		Required for tetramerization. /evidence=ECO:0000269|PubMed:19345194	302..366		59/63 (94%)