DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HOMER1 and Homer1

DIOPT Version :10

Sequence 1:NP_004263.1 Gene:HOMER1 / 9456 HGNCID:17512 Length:354 Species:Homo sapiens
Sequence 2:XP_036013945.1 Gene:Homer1 / 26556 MGIID:1347345 Length:382 Species:Mus musculus


Alignment Length:364 Identity:347/364 - (95%)
Similarity:351/364 - (96%) Gaps:12/364 - (3%)


- Green bases have known domain annotations that are detailed below.


Human     3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTF 67
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    19 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTF 83

Human    68 TKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESA 132
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    84 TKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESA 148

Human   133 GGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSH------------SSAISKHWEA 185
            |||||||||||||||||||||||||||||||||||||||||.|            ||||||||||
Mouse   149 GGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFPHSAGDRTQALSHASSAISKHWEA 213

Human   186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELN 250
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||
Mouse   214 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHSHKTELN 278

Human   251 QTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKS 315
            ||:||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   279 QTVQELEETLKVKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKS 343

Human   316 QNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
            ||||||||:||||||||||||||||||||||||||||||
Mouse   344 QNEQEAFRSNLKTLLEILDGKIFELTELRDNLAKLLECS 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOMER1NP_004263.1 EVH1_Homer_Vesl 3..111 CDD:269917 107/107 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..173 58/58 (100%)
Smc <181..>352 CDD:440809 166/170 (98%)
Required for tetramerization. /evidence=ECO:0000250|UniProtKB:Q9Z214 290..354 62/63 (98%)
Homer1XP_036013945.1 EVH1_Homer_Vesl 19..127 CDD:269917 107/107 (100%)
Smc <209..>380 CDD:440809 166/170 (98%)

Return to query results.
Submit another query.