DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOMER1 and Y60A3A.16

DIOPT Version :10

Sequence 1:NP_004263.1 Gene:HOMER1 / 9456 HGNCID:17512 Length:354 Species:Homo sapiens
Sequence 2:NP_001370082.1 Gene:Y60A3A.16 / 190438 WormBaseID:WBGene00013364 Length:142 Species:Caenorhabditis elegans


Alignment Length:136 Identity:31/136 - (22%)
Similarity:58/136 - (42%) Gaps:27/136 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    34 ARTVFSDSQLSGLEKRFE-IQRYLS-TPERV-ELATALS---------LSETQVKTWFQNRRMKH 86
            ||.:.|......:::..| :.|:|| ..:|| |:..|::         .:|:......:|..:..
 Worm    60 ARVLESQRNFQVVDENVELVDRFLSEEADRVYEVDEAVTGNAKICGDREAESSAAASSENYVIAE 124

Human    87 KKQLRKSQDEPKAADGPESPEGSPRAPEGAPADARLSLPAGAFVLTEPEDEV-DIGDEG---ELS 147
            :..|.:.|||  .:|..|:...|..:||...|:.         :.::.::|| ::|..|   ...
 Worm   125 EVILVRGQDE--QSDSAEAESISSVSPENVVAEE---------IKSQGQEEVTELGRSGCVENEE 178

Human   148 SGPHVL 153
            ||..||
 Worm   179 SGGDVL 184

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOMER1NP_004263.1 EVH1_Homer_Vesl 3..111 CDD:269917 20/88 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..173 10/44 (23%)
Smc <181..>352 CDD:440809
Required for tetramerization. /evidence=ECO:0000250|UniProtKB:Q9Z214 290..354
Y60A3A.16NP_001370082.1 AMPKA_C_like 44..140 CDD:473060 18/81 (22%)
Blue background indicates that the domain is not in the aligned region.

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