Protein Alignment HOMER1 and K02E10.7

DIOPT Version :10

• Sequence 1: NP_004263.1
• Gene: HOMER1 / 9456
• HGNCID: 17512
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001360081.1
• Gene: K02E10.7 / 186892
• WormBaseID: WBGene00019321
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 145
• Identity: 27/145 - (18%)
• Similarity: 55/145 - (37%)
• Gaps: 44/145 - (30%)

Human     2 GEQPI--------FSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDG------ 52
            |||.:        :..:..||.:: |.:|.|            ..|.|| :.:....||
 Worm   368 GEQQVLTEPVPKKYHKKFAVFAME-NVRKEW------------DNDITR-IEKCKLRDGSMCLRI 418

Human    53 ---------SKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKE 108
                     |.:|.|..|...:  .:|.::|....|:..::.:|     ::.|..|..:..|.:.
 Worm   419 VIPAKDEIASSSIFNRIIKSRL--GQTIKRFRSHQDTVVDSDFG-----DYALMNFRRENTEIEV 476

Human   109 AARLAKEKSQEKMEL 123
            |..:.|..::::::|
 Worm   477 ARNMPKFTNKQQVQL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER1	NP_004263.1	EVH1_Homer_Vesl	3..111	CDD:269917	24/130 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..173		2/10 (20%)
		Smc	<181..>352	CDD:440809
		Required for tetramerization. /evidence=ECO:0000250|UniProtKB:Q9Z214	290..354
K02E10.7	NP_001360081.1	Protein Kinases, catalytic domain	52..300	CDD:473864