DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HOMER1 and homer1

DIOPT Version :10

Sequence 1:NP_004263.1 Gene:HOMER1 / 9456 HGNCID:17512 Length:354 Species:Homo sapiens
Sequence 2:NP_001106603.1 Gene:homer1 / 100127824 XenbaseID:XB-GENE-5807410 Length:355 Species:Xenopus tropicalis


Alignment Length:355 Identity:328/355 - (92%)
Similarity:347/355 - (97%) Gaps:1/355 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNM 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||
 Frog     1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTISPNM 65

Human    66 TFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQE 130
            |||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||
 Frog    66 TFTKTSQKFGQWADSRANTVYGLGFSSEHHLTKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQE 130

Human   131 SAGGDLQSPLTPESINGTDDER-TPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNN 194
            |||||||||||||||||||||| |||||.|||||||||||||||:|||||:||||||||||||||
 Frog   131 SAGGDLQSPLTPESINGTDDERTTPDVTPNSEPRAEPTQNALPFTHSSAINKHWEAELATLKGNN 195

Human   195 AKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
            |||||||||||||||||||||||||||||||||||:||||:|:|||||.:|||||||.|||||.|
 Frog   196 AKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVSELECLSNQANAVQSHKTELNQKIQELETT 260

Human   260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRN 324
            ||.|||||||||:|:::|:|||:|:|||:|||||||..|||:||||||||||||||||||:||||
 Frog   261 LKKKEEEIERLKEEVEHAKELQDQKDSLSQKLQEVETHNKDMEGQLSDLEQRLEKSQNEQDAFRN 325

Human   325 NLKTLLEILDGKIFELTELRDNLAKLLECS 354
            ||||||||||||||||||||||||||:|||
 Frog   326 NLKTLLEILDGKIFELTELRDNLAKLIECS 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOMER1NP_004263.1 EVH1_Homer_Vesl 3..111 CDD:269917 105/107 (98%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..173 57/59 (97%)
Smc <181..>352 CDD:440809 150/170 (88%)
Required for tetramerization. /evidence=ECO:0000250|UniProtKB:Q9Z214 290..354 58/63 (92%)
homer1NP_001106603.1 EVH1_Homer_Vesl 3..111 CDD:269917 105/107 (98%)
SMC_prok_B <185..334 CDD:274008 128/148 (86%)

Return to query results.
Submit another query.