Protein Alignment HOMER2 and PRR1

DIOPT Version :10

• Sequence 1: XP_006720838.1
• Gene: HOMER2 / 9455
• HGNCID: 17513
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_012806.1
• Gene: PRR1 / 853744
• SGDID: S000001599
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 65/365 - (17%)
• Similarity: 113/365 - (30%)
• Gaps: 131/365 - (35%)

Human   109 FAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTD--------------- 158
            |.:...:..|.|.|.::..::|...|:..:....|.||.:....:.....
Yeast    21 FPDSIGDQHEKALIDENGEEDKKMASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGN 85

Human   159 ------DEKASHAGPANTHLKSENDKLKIALTQ----------SAANVKKWE-IELQTLRE---- 202
                  |:.:.:.....:|.:..:|.|.:  ||          :.||:.... :.|.|:.|
Yeast    86 LSMSPIDQSSLNIPKRRSHARLLDDMLSV--TQPNQRVVSELIAPANLSPQRVVSLPTVTEEALV 148

Human   203 ------SNARLTTALQESAASVEQ-------------------WKR-------------QFSICR 229
                  .|........||::|.|:                   ||:             .:.:..
Yeast   149 NDSVDSDNYTKEPYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMD 213

Human   230 DENDRLRNKIDELEEQCSEINREKEKNTQL--KRRIEELEAELREKETELKDLR----------- 281
            ..|.:|:....:..:...|::..::.||.|  |..:..||..|..:...||.|.
Yeast   214 QSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGIN 278

Human   282 ----------------KQSEIIP---QLMSECEYVSEKLEAAERDNQNLE---------DKVRSL 318
                            |....:|   .:||.|. ..:.|.|....|..||         :.|.::
Yeast   279 NPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCP-AGDLLAAVMARNGRLEAWLIQRIFTEVVLAV 342

Human   319 KTDIEESKYRQRHLKVE---LK-SFLEVLDGKIDDLHDFR 354
            |. :.|:....|.||:|   || ||        ||::.||
Yeast   343 KY-LHENSIIHRDLKLENILLKYSF--------DDINSFR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER2	XP_006720838.1	EVH1_Homer_Vesl	13..121	CDD:269917	2/11 (18%)
		SMC_prok_B	<103..343	CDD:274008	61/352 (17%)
PRR1	NP_012806.1	S_TKc	192..508	CDD:214567	40/192 (21%)