Protein Alignment HOMER2 and Y60A3A.16

DIOPT Version :10

• Sequence 1: XP_006720838.1
• Gene: HOMER2 / 9455
• HGNCID: 17513
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_001370082.1
• Gene: Y60A3A.16 / 190438
• WormBaseID: WBGene00013364
• Length: 142
• Species: Caenorhabditis elegans
• Alignment Length: 283
• Identity: 61/283 - (21%)
• Similarity: 101/283 - (35%)
• Gaps: 67/283 - (23%)

Human    41 TNEVTRIYNVIGTLRG--------------AVEPDRYVILGGHRDSWVFGGIDPQSGAA------ 85
            :.|..|:|.|...:.|              |...:.|||.   .:..:..|.|.||.:|
 Worm    84 SEEADRVYEVDEAVTGNAKICGDREAESSAAASSENYVIA---EEVILVRGQDEQSDSAEAESIS 145

Human    86 ------VVHEIVRSFG-----TLKKEGWRPRR----TILFASWDAEEFGLLGSTEWAEENSRLL- 134
                  ||.|.::|.|     .|.:.|.....    .:|.|  ::||..:..|:...||:....
 Worm   146 SVSPENVVAEEIKSQGQEEVTELGRSGCVENEESGGDVLVA--ESEEVRVEKSSNMVEESDAEAE 208

Human   135 -QERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEF 198
             :|:....|..|...||  ..|.:......:.|:.|.:..|:.:.|.|.|.            |.
 Worm   209 NEEKTELTIEEDDDWEG--IERSELEKAFAAAVNLLEESGKAEEIGAEAKM------------EL 259

Human   199 SGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFK 263
            .|:.:|:..||..:.:.....:   |.||::.. |:  |........::.:...||.|....:.|
 Worm   260 FGLHKIATEGSCREAQPMAVMI---SARAKWNA-WQ--KLGNMSQEEAMEQYLALVSKEIPGLTK 318

Human   264 YHLTVAQVRGGMVFELANSIVLP 286
            ...||     |.:.|:..|:.||
 Worm   319 AGHTV-----GKMSEMETSVGLP 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER2	XP_006720838.1	EVH1_Homer_Vesl	13..121	CDD:269917	25/114 (22%)
		SMC_prok_B	<103..343	CDD:274008	40/190 (21%)
Y60A3A.16	NP_001370082.1	AMPKA_C_like	44..140	CDD:473060	13/58 (22%)